Sabine has had diabetes for well over a year, and she used to need insulin injections once or twice a day. When she began to show hairloss signs of a second adrenal tumor, Dr. Anna Edling and I agreed she would do better with Lupron injections than surgery. The Bean just turned 7 and is not strong. Dr. Edling told me at the time we began the Lupron injections that it might help control Bean's diabetes, and she asked me every month whether I was seeing an improvement. After three months, Sabine only needed insulin once a day for maybe half the days in the month. In the fourth month, she only needed insulin at most a third of the month. In the fifth month, she didn't need insulin at all. I thought there was an equal chance that she had an insulinoma growing on her pancreas again, but I now think I was wrong. I skipped her last Lupron shot at the beginning of June, and within a few days Sabine's sugar (I measure it in her urine, not her blood) was high up there. Fortunately for Sabine, Dr. Edling had a few extra doses frozen (a new vial would be way expensive), and she gave her a shot a week ago. In three days, the sugar level was coming down and today she didn't need insulin at all. Her blood sugar is still on the high side, but I can't test that. I go by her urine and this seems to be enough to keep her active and feeling pretty good. Dr. Edling says she has seen this in another ferret with diabetes. Has anyone else observed this? Blessings Judith [Posted in FML issue 3458]