The Vulvar swelling should go down, but it does take a while. Spaying a female in heat is not likely turning off a light switch - the levels of estrogen are high and may take weeks to reach normal level. Also, the structural changes to the vulva in terms of increased ground substances between the normal connective tissue, which is a result of the hyperestrogenism, need to be broken down and removed. I doubt that there is anything else going on here just yet. With kindest regards, Bruce H. Williams, DVM, DACVP Join the Ferret Health List at http://groups.yahoo.com/group/Ferret-Health-list [Sukie note: ground substances are a gel-like material in which connective tissue fibers and cells are imbedded.] [Posted in FML issue 3439]