> 1. what is the top dosage of Pediapred that I can give There isn't a max dosage - it varies with individuals - some may ulcerate on a lower dosage - some may never ulcerate. I've had ferrets on 5mg lb as part of palliative therapy for lymphoma who never had a problem with the dosage - and one that ulcerated on that dosage. > 2. should I just let nature take its course and let him get to the > point where he is seizeing, or should I help him cross. You have presented a good case that he is not enjoying life - that is my personal Rubicon. I believe in relieving suffering, not waiting until clinical signs are incompatible with life. Ask yourself this question - are you keeping him alive because he enjoys life, or for some other reason. If you can answer that, then you will know what your course of action should be. Jonesy didn't give up before when he had surgical problems - he knew something. If he's stopped fighting now; perhaps he knows something as well. This decision is not an easy one, but one that you have to be absolutely convinced of - because you don't want to wonder "what if" five years down the road. Be sure, and be decisive. With kindest regards, Bruce Williams, DVM [Posted in FML issue 3464]