The diagnosis of kidney failure and anemia may go hand in hand, as the kidney is the site of production of a hormone which regulates RBC production (erythropoetin), but unfortunately without access to the specific CBC values and values from the kidney it is difficult to establish either the renal failure or it's possible causation of the anemia. EpoA (a synthetic erythropoetin) is certainly a viable option for anemia in ferrets, however, it's use in chronic renal failure should be tempered with the advice that it only treats one symptom of a multifacorial organ failure. If you can provide the definitive values for the CBC and chronic renal failure, it may help decide this issue. Right now, EpoA won't hurt, but it's long-term benefits, especially in this case, require more information. With kindest regards, Bruce Williams, DVM [Posted in FML issue 3408]