Actually I beg to differ. I am a breeder and I have 13 unfixed females, which is why I referred to them as "jills" BTW. ALL of them either came from out of the country or are 1st and 2nd generation American born OF imported lines. You comment about *our* attitude here and all our ferrets being fixed. Well, I never have seen a case of Aplastic Anemia in a fixed female. When I speak of all the ones I have seen over the past 15 years, they were all unfixed rescues. I also am friends with and talk to many breeders and rescuers overseas regarding practices and problems and Aplastic Anemia IS a threat to unfixed female ferrets worldwide, it is NOT an "American thing". "The big 3"? I missed that but I assume you mean Adrenal, Insulinoma and Aplastic Anemia. Yeah we have more of the first two here, and there are many theories as to why, early altering, lighting, difference in diet etc. None of those factors matter with Aplastic Anemia. It IS a medical fact in EVERY country. In fact we likely see far LESS of that on in America since most pet ferrets ARE already fixed. Granted no, not every single jill will get it and die. There is one in 20 or 25 which seems to not be susceptible to it. But the fact remains, you won't know if yours is or not until or unless she becomes sick. I don't consider that a good risk to take. Why don't you join the International rescuer, breeding or medical lists and see for yourself what owners, breeders, rescuers and vets FROM outside America say? YOU are the only one making this an "issue" between American and non-American ,,,,,, ummmmm,,,, *beliefs*.... and seems to have an attitude of vets as money hungry liars. [Posted in FML issue 3356]