Murray wrote: >I treated him with Ivamec oral and thought I had got on top of it. But >maybe not as I can not see into his cauli ear. He lost an awful lot of >weight and then lost the use of his back legs. ......Shortly after he >took ill I noticed He had quite bad ear mites. I gave both these boys a >good dose of Ivomec oral. Coincidence i suppose, but they did start to >improve and, well, I just wondered if earmites could trigger a >neurological responce. Inflammation resulting from severe ear mite infection can result in middle and inner ear infections in rare cases and resultant neurological signs - head tilt, difficult walking, etc. Plus a cauliflower ear - may be a severe ear infection... However, you mention hindlimb weakness and weight loss - not what you would expect with ear mites. Unfortunately, these are very non-specific signs, and can be due to any number of diseases, and I don't think that you should stop your search here. The other ferret exhibited activity which suggests seizures, so a good physical with a blood glucose is probably in order. Regarding the possibility of ivermectin toxicity - it is probably unlikely, because ivermectin has a fair margin of safety, but you mention a "good dose of ivermectin". What exactly consitutes a good dose? With kindest regards, Bruce Williams, dVM [Posted in FML issue 3323]