Dr. Williams and everyone who emailed me privately, Thank you all for your responses to my dilema. Being the ultra-paranoid ferret mommy that I am, I called my vet to get his opinion on Smokey and her "sudden" nipple appearance. She is eating, drinking, and sleeping fine, has no hair loss, and is energetic as always. The vet still suggested bringing her in and checking for adrenal, so tomorrow we go to the vet. Bandit of course will tag along for moral support. Please keep your fingers crossed and Smokey in your heart that all is well with her. I know it is a personal decision, but my little ones will need to be going for their vaccines soon. They were fine for the first two years, then last year Bandit had a reaction. Luckily we weren't very far from the vet office when he started throwing up. We took him back to the vet and they monitored him, but they said it wasn't a severe reaction. They told us our options for next time were to not vaccinate, vaccinate with benadryl beforehand, or vaccinate normally and keep him there to monitor. I know a lot of folks have mixed feelings on this, but any input would be appreciated as we just want to do what is best for our fuzzy furrballs. I have been agonizing over this decision for over a year now and feel I am nowhere closer to a resolution :( Thanks for the help! Christine and the fuzzy angels, Smokey and Bandit [Posted in FML issue 3259]