Dear Kim: Adrenal cryosurgery in ferrets is a fairly new development - only being used for a year or so. Dr. Charlie Weiss was the first to use this technique widely, and he has made the technique available in a video Common Ferret Surgical Procedures - Insulinoma and Adrenal Disease, available for sale on his web site: http://www.ferretdoctor.com/video.html He has also published his findings in the following articles: Cryosurgery of the Ferret Adrenal - Exotic DVM Magazine, 1(5), 1999, p. 27 and 28 and Cryosurgery Therapy of Hyperadrenocorticism in Ferrets - Vet Forum, 42-44. It may not fit a strict definition of peer-reviewed, but the technique has certainly been widely publicized. Unfortunatley, I cannot speak to complications associated with the procedure, but Charlie has told me that they are considerably lower than traditional surgical techniques. With kindest regards, Bruce Williams, DVM [Posted in FML issue 3196]