Now and then we discuss hypothetical possible contributors to hormonal neoplasias and abnormalities, since they might have reflections in hormonal growths,such as adrenal neoplasias, in ferrets. In the latest volume (158, Sept. 9, 2000) of Science News there is an article titled "Girls May face Risks from Phthalates". The article is about unusually early breast development (as early as 6 months). Phthalates are referred to as "a family of ubiquitous pollutants" ... used in the manufacture of many products, among them, plastics, lubricants, and solvents." It goes on to discuss a study of baby nutrients (formulae and foods) by a Danish institute which found them in baby food and formulas. There was also the possibility of fetal exposure mentioned. Interestingly, a recent study of the breakdown products found that solvents in cologne were the largest contributor for women. This interests me in relation to perfumed products for ferrets. We use perfume now and then when there is a status difficulty, but we do this only on very temporary bases. Have to winder if the regular application of scents or scented grooming products might join the already large group of possible contributors to adrenal growths. One of the phthalates discussed is also seen in dyes, fingernail polish, and food wraps, among other things. They show up in many items. In the girls the ones with the highest concentrations were more likely to have premature development and visa versa. These may still turn out to not be a culprit in the developmental aberration, let alone in ferret problems, but this gives a feel for how complex the picture may be for possible contributing factors to adrenal neoplasias: perfumes, plastics that have estrogen imitators, too little full darkness, diet, lack of exercise, and pesticide exposure are among the things which might work alone or in conjunction with something as basic as neutering. Don't know if this is yet at the Science News web site but watch http://www.sciserv.org if interested. [Moderator's note: Not all articles will apppear on the web site... BIG] [Posted in FML issue 3172]