Thanks to those who annswered me but I guess I didnt say something very important. I don't know if it makes a difference or not but Snickers did get a liquid benadryl before the distemper shot. So what do we do next year, is the benadryl shot more powerful? Will that help? or do I give her liquid benadryl for 4 days in a row before the shot? yikes what do I do? She is doing ok now. Snowy isnt much better. He has lost another oz, I think due to not eatting enough. I called the vet and now we are giving him pepsid-ac instead of peptol and I am putting him back in the cage with the others, they are comforting him. Plus I am giving duck soup. Hopefully this will give him less stress, and more food. thanks for the help Lydia and the crew Snickers, Casper, Bubba, Trooper, Smokey, Mr. Snowman http://www.HLRConnect.com/ferrets/ [Posted in FML issue 2991]