As I have come to expect (with satisfaction), Bob C. has offered words for thought and consideration. Which, in my opinion is the purpose of any discourse. Insulinoma is a frightening disease, as is adrenal disease, specifically due to the fact that a 'pill' or simple surgery will not (in all odds) cure it's presence, although adrenal operations have a higher success rate than insulinoma. I try to approach Insulinoma in a similar manner that one would treat diabetes ... and after 6 months (and with Jake originating from 'MF'), we have had some success!! And not without help from this List!!!!! Bob C: By the way ... Is there a connection between Insulinoma and early neuters? What is the relation (if any) between pancreatic (sp) function and hormone function? I find myself wondering if an animal neutered at 6 weeks (as I have been told MF does, but wonder if this could be true!?!), if such a soul would be able to develop sufficiently to function?! I would want to see MF research, since their's is a 'bottom-line' industry, and I would like to see if MF is working on this issue. After Jake was Dx, I did a bunch of research. Jake's 1st vet didn't offer any treatment, and merely stated that he had the disease and would (shortly) suffer it's course. Research suggested that a high protein diet is crucial in order to manage the level of insulin in the system. So I found another 'fert-oriented' vet, and together we crafted Jake's tx! Right now, Jake is on a strict hi-protein diet, with Brewer's yeast and a herbal supplement, recommended by MJO on this List. Since 8/99, Jake is doing well. Of course, Jake has to get up q 4-6 hours (as do I!), and he doesn't get any 'furro-vite' like he used to! But he is still 'war-dancing'! Anyhow ... Since Dx, Jake has been doing well on his diet, and fasting blood sugar hasn't been below '90' since first Dx. Because this is an "N" of '1', it maybe merely by chance. I would welcome any differences of opinion!! [Posted in FML issue 2924]