http://www.smartgroups.com/message/readmessage.cfm?gid=1423922
&messageid=6257&startid=6259
 
Sounds like you have several questions about Sam, so I will try to answer
them all.  If the adrenal glands and prostate were enlarged on the
ultrasound and he is having urination problems, then surgery is the best
option.  However if your vets are unwilling to do surgery perhaps you
should check with the vet school in Berlin, if that is possible.  If that
is not possible then what I would recommend for medical treatment is
Lupron depot (leuprolide acetate), Propecia or Proscar (finasteride), and
an antibiotic (Baytril enrofloxicin).  Lupron will stop the stimulation
(LH) to the adrenal glands.  Thus they will stop overproducing the
adrenal sex hormones.
 
Propecia/Proscar will stop the testosterone from being converted to
dihydrotestosterone (DHT).  Dihydrotestosterone is the hormone that is
believed to cause the prostate to become enlarged.  Without DHT the
prostate shrinks.
 
Baytril is a good antibiotic that reaches the prostate and is good
against the likely bacterial infection.
 
Melatonin is also a good product.  There are actually melatonin receptors
on the prostate.  I would use it with Lupron, Propecia, and Baytril.  The
recommended dose is 1mg of melatonin orally about 8-9 hours after
sunrise, or to use the male mink melatonin implants every 4-6 months.
 
Hope that helps,
Jerry Murray, DVM
Dallas, Texas
[Posted in FML issue 4296]