Hi folks

Recently a young male I took in showed a vigirous Red Rash on his
stomach, a high temperature, and papules on his belly from front legs
to back legs.

A histology and Complete Blood Count were done and I include these in
this post. He was treated with Antibiotics and Steriods which didn't
seem to have much effect tho he has now got his fur back, has put on
weight and is again playing and running about. He was lethargic lost
some weight and only stayed up to play for about 20 minutes at a time.

If anyone has experienced similar or has some ideas please contact me
via my email or by posting on the FML. This has stumped a few ferret
knowledgeable people/vets.

Possible theories
Contact Allergy, Hormonal. ?

Many thanks in advance

FurHuggles
Michelle


Hi Michelle

Here are Widgets results. Thanks for the photos, 

OWNER            

SPECIES          FERRET
BREED N/A
SEX      MALE 
AGE     2 YEARS
DATESENT       06/06/2009
DATERECEIVED   06/06/2009
DATESIGNEDOUT  06/06/2009
SUBMITTER      [xxx] 
VET      JENNI 
TECHNICIAN     RAY 
LABORATORY  LABADDR1       

RESULTS

WBC      11.0  x10^9^/L             ( 2.5 -15.4 )
RBC       7.4  x10^12^/L            ( 6.8 -12.2 )
HB      126    g/L                  ( 120 - 174 )
HCT            L/L                  ( 0.36 - 0.51 )
MCV      53    fL                   ( 51 - 53 )
MCH      17    pg                   ( 9.2 - 18.6 )
MCHC    320    g/L                  ( 231 - 351 )
PLAT    See below     x10^9^/l
SEGN    51%    5.61   x10^9^/L      (2.8 - 8.3 )
LYMPH   40%    4.40   x10^9^/L      (1.1 - 6.3 )
MONO     4%    0.44   x10^9^/L      (0.2 - 0.6 )
EOSIN    5%    0.55   x10^9^/L      (0.08 - 0.6 )

@COMMENTS

RESULT COMMENTS

BLOOD FILM COMMENTS:

Red cells normal.

Unable to report an accurate platelet count due to clumping, however
numbers appear adequate.

Thank you for the fresh blood smear.

HISTOLOGY OF SKIN BIOPSY

HISTOPATHOLOGIC FINDINGS.

Sparsely haired skin. The tissue fragments are somewhat torn. There is
marked epidermal acanthosis with the stratum spinosum being up to four
cell layers deep, and marked epidermal hyperplasia with the stratum
basale being three to four cell layers deep. There is hyperplasia of
follicular epithelium. There is a moderate infiltrate of lymphocytes
and a few neutrophils forming a band in the superficial dermis
subjacent to the basement membrane and lining hair follicles. There is
sometimes exocytosis of leukocytes across the epidermis. Apocrine sweat
glands are dilated by secretion, lined by hyperplastic epithelium often
with transmigrating neutrophils and sometimes replaced by necrotic
debris.

There is moderate atrophy of some hair follicles.

DIAGNOSIS.

Sparsely haired skin: marked epidermal acanthosis and hyperplasia,
follicular epithelial hyperplasia, band-like mild superficial
lymphocytis and neutrophilic dermatitis and apocrine sweat gland
adenitis with cystic dilation and epithelial hyperplasia.

[Posted in FML 6390]