Lupron is safe even in the absence of hyperestrogenism.
 
There is really no specific in-house test that your vet can run to
establish the presence or absence of adrenal disease.  Unlike dogs, where
you can pick up some specific clues, if you want a definitive diagnosis
via bloodwork, then you need to run the UT panel.  There is no marker in a
CBC that will identify hyperestrogenism - there are some changes that may
suggest it, but none that will diagnosis it.  The money is better spent
getting the UT test - three Lupron injections given to a ferret that
doesn't need them is far more expensive.
 
With kindest regards,
Bruce H. Williams, DVM, DACVP
 
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[Posted in FML issue 3452]