1. Vet Pathol. 2010 May 13. [Epub ahead of print]
Multicentric Squamous Cell Carcinoma In Situ Associated With
Papillomavirus in a Ferret.
Rodrigues A, Gates L, Payne HR, Kiupel M, Mansell J.
A 6-year-old castrated male ferret presented with multiple black
and tan proliferative skin lesions. Histologically, the lesions were
characterized by multifocal plaques of irregular epidermal hyperplasia
and full-thickness dysplasia, with loss of normal epithelial
stratification, loss of nuclear polarity, and rare eosinophilic
intranuclear inclusion bodies in the superficial layers of the
epidermis. Immunohistochemical staining with a monoclonal
antibody against papillomaviruses was strongly immunoreactive.
Ultrastructurally, large numbers of hexagonal viral particles
approximately 50 nm were observed within the nuclei of dysplastic
superficial keratinocytes. To the authors' knowledge, this is the
first report of a ferret multicentric squamous cell carcinoma in
situ associated with papillomavirus.
PMID: 20466863 [PubMed - as supplied by publisher]
That group helping ferrets:
http://www.ferrethealth.msu.edu/
Sukie (not a vet)
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/http://ferrethealth.org/archive/http://www.afip.org/ferrets/index.htmlhttp://www.miamiferret.org/http://www.ferrethealth.msu.edu/http://www.ferretcongress.org/http://www.trifl.org/index.shtmlhttp://homepage.mac.com/sukie/sukiesferretlinks.html
all ferret topics:
http://listserv.ferretmailinglist.org/archives/ferret-search.html
"All hail the procrastinators for they shall rule the world tomorrow."
(2010, Steve Crandall)
[Posted in FML 6700]
