Parasitol Res. 2008 Apr 3 [Epub ahead of print]
Efficacy of imidacloprid 10%/moxidectin 1% (Advocate(R)/Advantage
Multitrade mark) against fleas (Ctenocephalides felis felis) on
ferrets (Mustela putorius furo).
Wenzel U, Heine J, Mengel H, Erdmann F, Schaper R, Heine S,
Daugschiess A.
Veterinary Practice Dr. Wenzel, Helenenstr. 26a, Leipzig, Germany.
Ferrets (Mustela putorius furo) are becoming increasingly popular as
pets and are kept in households with other pet animals such as dogs and
cats, from which they may catch flea infestations with the predominant
flea species Ctenocephalides felis. In this study, the efficacy of
imidacloprid/moxidectin spot-on (Advocate(R)/Advantage Multitrade mark)
was investigated in the therapy and prevention of flea infestation in
ferrets. Sixteen adult ferrets of varying weights and ages and of both
sexes were included. Ferrets were infested with 50 fleas each on days
-7, -1, 7, 14, 21, and 28. On study day -6, the animals were randomized
into two groups based on body weight and flea count. Each ferret
allocated to group 1 was treated with 0.4 ml of imidacloprid
10%/moxidectin 1% (Advocate(R)/Advantage Multitrade mark). The ferrets
in group 2 remained untreated. Flea counts were performed by combing
24 to 48 h after infestation. The primary efficacy criterion was the
reduction in the number of fleas at each time point post treatment
compared to the ferrets in the untreated control group. On day 1, the
therapeutic efficacy was 100%. The preventative efficacy was 100% at 1
and 2 weeks post treatment, and it was >97% and >90% at 3 and 4 weeks
post treatment. No local or systemic side effects were observed in any
of the ferrets treated.
PMID: 18386063 [PubMed - as supplied by publisher]
Sukie (not a vet)
Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/fhc/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
[Posted in FML 5933]
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