I have used both the Topspot and the spray on my ferrets at different times--
The spray is easier to gauge, because it is 1 spray per pound when you use
the large bottle, more if you use the smaller spray.  I now use Topspot--I
buy the 44-88 lb size, draw up the amount from one of the vials into a
syringe, and divide that amount by 60--that is the mid-range for that size,
and I divide it among by three dogs (small terriers) and my four ferrets--
they get literally about 2-3 drops between their shoulder blades every 45-60
days.  I can tell you that it really really works!
 
For most people the spray is the best way to go, one SMALL bottle would last
a long time with several ferrets, and you can re-spray every 30 days if
needed, but I doubt you will--I am on a 2 month schedule here at the house,
and I haven't seen an itch for almost a year! (and I live in flea and tick
country--central Texas.)
 
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Amy M.E. Cada                            [log in to unmask]
Behavioral Neuroscience, UT Austin
Asta- 2/3 NA agility, tennis ball, flyball, and bath addict scottie;
Wylie-court jester wire fox; and their 4 geriatric ferret friends
Gryphon--vocal, rambuncious, teenager scot!
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[Posted in FML issue 1822]