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Subject:
From:
Sukie Crandall <[log in to unmask]>
Date:
Thu, 31 Jul 2014 12:44:29 -0400
Content-Type:
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This might be a very new one:

http://www.ncbi.nlm.nih.gov/pubmed/25075826

QUOTE

J Am Vet Med Assoc. 2014 Aug 15;245(4):419-424.

Suspected primary hypoparathyroidism in a domestic ferret (Mustela
putorius furo).

de Matos RE1, Connolly MJ, Starkey SR, Morrisey JK.

Abstract
Case Description - A 4-year-old castrated male domestic ferret (Mustela
putorius furo) was examined because of a 3-week history of intermittent
seizures, signs of depression, hypocalcemia, and hyperphosphatemia.

Clinical Findings - Plasma biochemical analysis confirmed
hyperphosphatemia (17.7 mg/dL) and low concentrations of total (4.3
mg/dL) and ionized (0.49 mmol/L) calcium. Serum parathyroid hormone
concentration (2.30 pmol/L) was low or in the low part of the reference
interval. Treatment and Outcome-Calcium gluconate was administered (2.0
mg/kg/h [0.9 mg/lb/h], IV), followed by a transition to administration
of calcium carbonate (53 mg/kg [24.1 mg/lb], PO, q 12 h) and
dihydrotachysterol (0.02 mg/kg/d [0.009 mg/lb/d], PO). Attitude of the
ferret improved and seizures ceased as blood calcium concentrations
increased. The ferret was reexamined because of seizures approximately
1 year after oral maintenance administration of dihydrotachysterol and
calcium was initiated. The ferret responded well to emergency and
long-term treatment but then was lost to follow-up monitoring. The
ferret died approximately 2 years after the initial evaluation and
treatment. Hypertrophic cardiomyopathy was diagnosed during necropsy,
but the parathyroid glands could not be identified.

Clinical Relevance - To the authors' knowledge, primary
hypoparathyroidism has not previously been reported in a ferret.
The condition should be considered for ferrets with hypocalcemia and
hyperphosphatemia without azotemia. Treatment with dihydrotachysterol
and oral supplementation of calcium appeared to be a viable option for
long-term management.

PMID: 25075826 [PubMed - as supplied by publisher]

END QUOTE

[Posted in FML 8162]


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