You might want to try a higher dose of Lupron Depot. Just as there are different durations for the depots there also is more than one possible dose. Trelstar/triptorelin pamoate depot is also under investigation in the U.S. (by Dr. Robert Wagner at Pitt) though no one know how well it will work. It is a compound similar to Lupron depot but different just as deslorelin is similar but different. From a friend's notes from the IFC Symposium the depot amount under study is 300 ug/kg IM q/ mo with an unknown effective length of time. I apologize that I do not have time to check that. 1 microgram (ug) = 0.001 milligram (mg). Adrenal disease itself can cause skin to become thin with sebaceous problems and bruising. Bruising also raises the question of whether the marrow is beginning to respond badly to the circulating hormones in which case people start thinking about things like Epogen, procrit, Arimidex, and sometimes transfusions. (Marrow transplants have even been done on ferrets for other things but trying that w high circulating levels of hormones likely would not make sense.) Now, to the meds you mention: Flutamide, Casodex and Propecia. Those are for treating enlarged prostates for ferrets who have those secondary to adrenal disease. See past FHL Archives posts like http://ferrethealth.org/archive/FHL2144 http://ferrethealth.org/archive/YPG1418 http://ferrethealth.org/archive/YPG1118 http://ferrethealth.org/archive/YPG971 http://ferrethealth.org/archive/SG15827 http://ferrethealth.org/archive/SG6795 etc. Hopefully, this will help some. Sukie (not a vet) Recommended ferret health links: http://pets.groups.yahoo.com/group/ferrethealth/ http://ferrethealth.org/archive/ http://www.afip.org/ferrets/index.html http://www.miamiferret.org/fhc/ http://www.ferretcongress.org/ http://www.trifl.org/index.shtml http://homepage.mac.com/sukie/sukiesferretlinks.html [Posted in FML 5774]
