Yes, this is a topic that has often come up on the FML. Whole males are the most likely ferrets to set off allergies and can do so in people who don't react to other ferrets. Sometimes those people are also allergic to cats. Sometimes afterward the allergy generalizes and the people react to any ferrets so a person has to watch for that. It doesn't happen always, obviously, and probably not even most of the time but it can happen. Sukie (not a vet) Recommended ferret health links: http://pets.groups.yahoo.com/group/ferrethealth/ http://ferrethealth.org/archive/ http://www.afip.org/ferrets/index.html http://www.miamiferret.org/ http://www.ferrethealth.msu.edu/ http://www.ferretcongress.org/ http://www.trifl.org/index.shtml http://homepage.mac.com/sukie/sukiesferretlinks.html all ferret topics: http://listserv.ferretmailinglist.org/archives/ferret-search.html [Posted in FML 6376]