John, while there are other possible causes I suspect that what you need to do is to open the Nov/Dec issue or Ferrets magazine to the article by Dr. Bruce Williams on Pemphigus. See also related posts in the FML and FHL archives: http://ferrethealth.org/archive/FHL1766 http://ferrethealth.org/archive/SG513 http://ferrethealth.org/archive/SG390 http://ferrethealth.org/archive/YG752 http://ferrethealth.org/archive/YG484 etc. Those are not all of the FHL ones, and I don't have time to check the FML Archives, too, but the FML Archives addy is in the header of every day's FML so that should help you! Sukie (not a vet) Recommended ferret health links: http://pets.groups.yahoo.com/group/ferrethealth/ http://ferrethealth.org/archive/ http://www.afip.org/ferrets/index.html http://www.miamiferret.org/fhc/ http://www.ferretcongress.org/ http://www.trifl.org/index.shtml http://homepage.mac.com/sukie/sukiesferretlinks.html [Posted in FML 5749]