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Subject:
From:
Sukie Crandall <[log in to unmask]>
Date:
Mon, 29 May 2006 11:32:03 -0400
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In PubMed there are over 800 articles found when that topic is
searched upon.
 
A recent study *might* fill in a very important blank which had existed
for knowing how getting enough exercise reduces malignancy rates (looked
at in other studies), or mortality during a malignancy (looked at in
this study), or both.  Studies already show that exercise reduces a
wide range of malignancy rates and improves survival.
 
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16299029&query_hl=2
&itool=pubmed_docsum>
 
>For the physically active, increasing IGFBP-3 by 26.2 nmol/l was
>associated with a 48% reduction in colorectal cancer specific deaths
 
From an Reuters article by Martha Kerr:
>insulin-like binding protein-3 (IGFBP-3), inhibits another protein
>called insulin-like growth factor-1 (IGF-1), thereby blocking IGF-1's
>proliferative effect on cell growth...
>
>Haydon told Reuters Health that that "physical activity can
>increase IGFBP-3 levels, which, in turn, reduces the amount of free
>IGF-1." IGF-1 has been shown to stimulate cell growth, inhibit cell
>death, and promote angiogenesis -- the formation of new blood
>vessels, which tumors need to grow...
>
>"Other studies that have looked at this have shown a dose-effect,
>meaning the more exercise the lower the risk...
 
While this was a human study there is a very reasonable chance of this
mechanism generalizing to other mammals and other types of malignancies.
 
Exercise is a very important part of health.
 
-- Sukie (not a vet, and not speaking for any of the below in my
private posts)
Recommended health resources to help ferrets and the people who love
them:
Ferret Health List
http://www.smartgroups.com/groups/ferrethealth
FHL Archives
http://ferrethealth.org/archive/
AFIP Ferret Pathology
http://www.afip.org/ferrets/index.html
Miamiferrets
http://www.miamiferret.org/fhc/
International Ferret Congress Critical References
http://www.ferretcongress.org
[Posted in FML issue 5258]

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