<http://www.smartgroups.com/message/readmessage.cfm? gid=1423922&messageid=16429&startid=16430> A mast cell tumor will not go away without surgery, so surgery is the first option. To help control the itchness, you can apply cortisone cream topically along with the pred and benadryl orally. Hope that helps, Jerry Murray, DVM --- Carried to the FML by -- Sukie (not a vet) Ferret Health List co-moderator http://www.smartgroups.com/groups/ferrethealth FHL Archives fan http://ferrethealth.org/archive/ replacing http://fhl.sonic-weasel.org International Ferret Congress advisor http://www.ferretcongress.org [Posted in FML issue 5141]